ONLY METFORMIN IS RECOMMENDED FOR THE PREVENTION OF TYPE 2 DIABETES. DIFFERENTIATE OR DIE ...
نویسندگان
چکیده
منابع مشابه
Metformin for prevention of type 2 diabetes.
OBJECTIVE To evaluate evidence from the medical literature that metformin is effective in preventing type 2 diabetes. DATA SOURCES Primary literature was accessed via a MEDLINE search (1966-December 2003) using the terms metformin, type 2 diabetes, and prevention. DATA SYNTHESIS Two studies evaluated metformin's potential to prevent type 2 diabetes, finding that metformin maintained or redu...
متن کاملPreventing, delaying, or masking type 2 diabetes with metformin in the diabetes prevention program?
The secondary analysis of the Diabetes Prevention Program (DPP) showed that withdrawal of metformin for 1-2 weeks resulted in a trend to a higher conversion rate from impaired glucose tolerance to diabetes as compared with the placebo group (1). This resulted in a reduction by 26% of the so-called prevention effect of metformin, i.e., from 31% in the primary analysis (2) to 25% in the secondary...
متن کاملMetformin in Type 2 Diabetes: Where is the Evidence?
Ever since the results of the UKPDS 34 study were published in 1998, metformin has been considered as the first-line pharmacological treatment for type 2 diabetes. However, from several standpoints the UKPDS study was methodologically questionable. The effectiveness of metformin with regard to microvascular and macrovascular complications has never been proven in a randomized double-blind place...
متن کاملWithin-trial cost-effectiveness of lifestyle intervention or metformin for the primary prevention of type 2 diabetes.
OBJECTIVE The Diabetes Prevention Program (DPP) demonstrated that intensive lifestyle and metformin interventions reduced the incidence of type 2 diabetes compared with a placebo intervention. The aim of this study was to assess the cost-effectiveness of the lifestyle and metformin interventions relative to the placebo intervention. RESEARCH DESIGN AND METHODS Analyses were performed from a h...
متن کاملThe prevention or delay of type 2 diabetes.
D iabetes is one of the most costly and burdensome chronic diseases of our time and is a condition that is increasing in epidemic proportions in the U.S. and throughout the world (1). The complications resulting from the disease are a significant cause of morbidity and mortality and are associated with the damage or failure of various organs such as the eyes, kidneys, and nerves. Individuals wi...
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ژورنال
عنوان ژورنال: Medicine of Ukraine
سال: 2019
ISSN: 1997-9894
DOI: 10.37987/1997-9894.2019.1(227).187538